Faculty

Wang, Tianli     


Research direction: (1) Catalyst Design & Development (2) New Synthetic Methodology (3) Active Target Driven Synthesis (4) Mechanistic Study

Contact information:

Email:

Homepage: https://www.chem-wang.com/

 

Curriculum Vitae

Since 2016.09   Full Professor at Sichuan University

2012.062016.08, Research Fellow with Prof. Yixin Lu, National University of Singapore

2011.082012.05Research Assistant, Institute of Chemistry Chinese Academy of Sciences (ICCAS)

2006.092011.07 PhD in Organic Chemistry with Prof. Qing-Hua Fan, Institute of Chemistry Chinese Academy of Sciences (ICCAS)

2002.092006.07 B.S. in Applied Chemistry with Prof. Xiaoming Feng & Prof. Qing-Hua Fan

 

Selected Awards and Distinctions

2019, ACP Lectureship Award (by Japan)

2019, Chengdu Specially-Appointed Professor, Chengdu Provincial Government

2018, Sichuan Specially-Appointed Professor, Sichuan province

2017, National 1000-Yong Talents Plan of China (2017)

2017, National 1000-Yong Talents Plan of Sichuan province (2017)

2017, Scientific Chinese “The People of the Year 2017 Awards (Youth)”

2016, Gold Award of Outstanding Mentor for “Singapore Science and Engineering Fair (SSEF) 2016”

2010, The Special Award for Young Scholars, ICCAS

2009, The Third ChemComm International Symposium “The Three Best Poster Prize”


Editorial/Advisory Board Memberships

Since 2020.06, Youth Editorial Board of Green Synthesis & Catalysis


Selected Publications

36. Lixiang Zhu, Xiaoyu Ren, Juan Du, Jia-Hong Wu, Jian-Ping Tan, Jixing Che, Jianke Pan, Tianli Wang*, “Transition metal-free multicomponent reaction towards constructing chiral 2H-1,4-benzoxazine scaffolds” , Green Chem., 2020, 22, 7506-7512.

35. Dongming Lu, Jia-Hong Wu, Jianke Pan, Xue Chen, Xiaoyu Ren, Tianli Wang*, "Asymmetric Synthesis of Benzothiazolopyrimidines with High Catalytic Efficiency and Stereoselectivity under Bifunctional Phosphonium Salt System", Chem. Commun., 2020, 56, 11231-11234.

34、Jian-Ping Tan#, Xiaojie Li#, Yuan Chen, Xianle Rong, Lixiang Zhu, Chunhui Jiang, Kai Xiao, Tianli Wang*, "Highly Stereoselective Construction of Polycyclic Benzofused Tropane Scaffolds and Their Latent Bioactivities: Bifunctional Phosphonium Salt-enabled Cyclodearomatization Process", Sci. China Chem., 2020, 63, 1091-1099.

33、Hongkui Zhang#, Chunhui Jiang#, Jian-Ping Tan, Hui-Lin Hu, Yayun Chen, Xiaoyu Ren, Hong-Su Zhang, Tianli Wang*, “Highly Enantioselective Construction of Fully-substituted Stereocenters Enabled by In-situ Phosphonium-containing Organocatalysis”, ACS. Catal., 2020, 10, 5698-5706 (Highlighted by Synfacts, 2020, 16, 967).

32. Xiaojun Yu, Song Zhang, Zhiyu Jiang, Hong-Su Zhang, Tianli Wang*, “Highly efficient and convenient access to phosphinates via CHCl3-assisted direct phosphorylation between R2P(O)H and ROH by phosphonium salt catalysis”, Eur. J. Org. Chem., 2020, 20, 3110-3113.

31. Juan Du, Jia-Hong Wu, Lixiang Zhu, Xiaoyu Ren, Chunhui Jiang, Tianli Wang*, "Bifunctional Phosphonium Salt-Catalyzed Enantioselective [4 + 2] Annulation of Isoindigos with Allenes: Access to Complex Heterocycles with Centerpiece of 4H-Pyrans", Adv. Synth. Catal., 2020, 362, 2510-2516.

30. Dongming Lu, Xin Liu, Jia-Hong Wu, Song Zhang, Jian-Ping Tan, Xiaojun Yu, Tianli Wang*, “Asymmetric Construction of BispiroCyclopropanePyrazolones via a [2 + 1] Cyclization Reaction by DipeptideBased Phosphonium Salt Catalysis”, Adv. Synth. Catal., 2020, 362, 1966-1971.

29. Xin Liu, Dongming Lu, Jia-Hong Wu, Jian-Ping Tan, Chunhui Jiang, Guowei Gao,* Tianli Wang*, “Stereoselective Synthesis of CF3-Containing Spirooxindoles via 1,3-Dipolar Cycloaddition by Dipeptide-Based Phosphonium Salt Catalysis”, Adv, Synth, Catal., 2020, 362, 1490-1495.

 

28. Jia-Hong Wu, Jianke Pan, Juan Du, Xiaoxia Wang, Xuemei Wang, Chunhui Jiang, Tianli Wang*, “Enantioselective Synthesis of Multifunctionalized 4H-Pyrans via Formal [4 + 2] Annulation Process by Bifunctional Phosphonium Salt Catalysis”, Org. Lett., 2020, 22, 395-399.

27. Jian-Ping Tan#, Hongkui Zhang#, Zhiyu Jiang, Yuan Chen, Xiaoyu Ren, Chunhui Jiang, Tianli Wang*, “Enantioselective Construction of Spiro[chroman-thiazolones]: Bifunctional Phosphonium Salt-Catalyzed [2 + 4] Annulation between 5-Alkenyl Thiazolones and ortho-Hydroxyphenyl- Substituted para-Quinone Methides”, Adv. Synth. Cataly., 2020, 362,1058-1063.

26. Chunhui Jiang#, Yayun Chen#, Hongkui Zhang, Jian-Ping Tan, Tianli Wang*, "Catalyst-Free Synthesis of a-Functionalized 2H-Chromenes in Water:ATandem Self-Promoted pseudo-Substitution and Decarboxylation Process", Chem. Asian. J., 2019, 14, 2938-2944.

25. Jianke Pan#, Jia-Hong Wu#, Hongkui Zhang, Xiaoyu Ren, Jian-Ping Tan, Lixiang Zhu, HongSu Zhang, Chunhui Jiang, Tianli Wang*,  “Highly Enantioselective Synthesis of Fused Tri- and Tetrasubstituted Aziridines: aza-Darzens Reaction of Cyclic Imines with α-halogenated Ketones Catalyzed by Bifunctional Phosphonium Salt”, Angew. Chem. Int. Ed., 2019, 58, 7425-7430.

24. Jian-Ping Tan#, Peiyuan Yu#, Jia-Hong Wu, Yuan Chen, Jianke Pan, Chunhui Jiang, Xiaoyu Ren, HongSu Zhang, Tianli Wang*, “Bifunctional Phosphonium Salt Directed Enantioselective Formal [4+ 1] Annulation of Hydroxyl-Substituted Quinone Methides with α-halogenated Ketones”, Org. Lett., 2019, 21, 7298-7302.

23. Lixiang Zhu#, Xiaoyu Ren#, Zhongxiu Liao, Jianke Pan, Chunhui Jiang, and Tianli Wang*, “Asymmetric Three-Component Cyclizations toward Structurally Spiro Pyrrolidines via Bifunctional Phosphonium Salt Catalysis”, Org. Lett., 2019, 21, 8667-8672.

22. Song Zhang#, Xiaojun Yu#, Jianke Pan, Chunhui Jiang,* Hongsu Zhang, Tianli Wang*, “Asymmetric Synthesis of Spiro-Structural 2,3-Dihydrobenzofurans via the Bifunctional Phosphonium Salt-Promoted [4 + 1] Cyclization of Ortho-Quinone Methides with α-Bromoketones”, Org. Lett., 2019, 6, 3799-3803.

21. Guofei Huang#, Xiaoyu Ren#, Chunhui Jiang, Jia-Hong Wu, Guowei Gao*, Tianli Wang*, “Efficient Synthesis of (E)-2-Nitromethylcinnamates via Phosphine-Catalyzed Tandem α-Addition and 1,3-Rearrangement”, Org. Chem. Front., 2019, 6, 2872-2876.

20. Jia-Hong Wu#, Jianke Pan#, Tianli Wang*, “Dipeptide-Based Phosphonium Salt Catalysis: Application to Enantioselective Synthesis of Fused Tri- and Tetrasubstituted Aziridines”, Synlett, 2019, 30, 2101-2106.


19. Tianli Wang, Xiaoyu Han, Fangrui Zhong, Weijun Yao, and Yixin Lu*, “Amino Acid-derived Bifunctional Phosphines for Enantioselective Transformations”, Acc. Chem. Res., 2016, 49,1369-1378.

 

18. Tianli Wang, Zhaoyuan Yu, Ding Long Hoon, Claire Yan Phee, Yu Lan, and Yixin Lu*, “Regiodivergent Enantioselective γ-Additions of Oxazolones to 2,3-Butadienoates Catalyzed by Phosphines: Synthesis of α,α-Disubstituted α-Amino Acids and N,O-Acetal Derivatives”, J. Am. Chem. Soc., 2016, 138, 265-271. (Highlighted by Synfacts, 2016, 12, 309)


17. Tianli Wang, Weijun Yao, Fangrui Zhong, Guo Hao Pang, Yixin Lu*, “Phosphine-Catalyzed Enantioselective γ-Addition of 3-Substituted Oxindoles to 2,3-Butadienoates and 2-Butynoates: Use of Prochiral Nucleophiles”, Angew. Chem. Int. Ed., 2014, 53, 2964-2968.


16. Tianli Wang, Fei Chen, Jie Qin, Yan-Mei He, Qing-Hua Fan*, “Asymmetric Ruthenium-Catalyzed Hydrogenation of 2- and 2,9-Substituted 1,10-Phenanthrolines”, Angew. Chem. Int. Ed., 2013, 52, 7172-7176. (Highlighted by J. org. Chem., 2013, 33, 2028)  


15. Tianli Wang, Lian-Gang Zhuo, Zhi Wei Li, Fei Chen, Zi Yuan Ding, Yanmei He, Qing-Hua Fan*, Jun Feng Xiang, Zhi-Xiang Yu*,  Albert S. C. Chan, “Highly Enantioselective Hydrogenation of Quinolines Using Phosphine-Free Chiral Cationic Ruthenium Catalysts: Scope, Mechanism and Origin of Enantioselectivity”, J. Am. Chem. Soc., 2011, 133, 9878-9891.


14. Tianli Wang, Zhaoyuan Yu, Ding Long Hoon, Kuo-Wei Huang, Yu Lan*, Yixin Lu*,  “Highly Enantioselective Construction of Tertiary Thioethers and Alcohols via Phosphine-Catalyzed Asymmetric γ-Addition reactions of 5H-Thiazol-4-ones and 5H-Oxazol-4-ones: Scope and Mechanistic Understandings”, Chem. Sci., 2015, 6, 4912-4922.


13. Tianli Wang, Ding Long Hoon, and Yixin Lu*, “Enantioselective Synthesis of 3-Fluoro-3-allyl-oxindoles via Phosphine-Catalyzed Asymmetric γ-Addition of 3-Fluoro-Oxindoles to 2,3-Butadienoates”,  Chem. Commun., 2015, 51, 10186-10189.


12. Tianli Wang, Ya Chen, Guanghui Ouyang, Yan-Mei He*, Zhiyan Li and Qing-Hua Fan*, “Solvent-Regulated Asymmetric Hydrogenation of Quinoline Derivatives in Oligo(Ethylene Glycol)s via Host-Guest Interactions”, Chem. Asian J., 2016, 11, 2773-2777.


11. Tianli Wang, Guanghui Ouyang, Yan-Mei He and Qing-Hua Fan*, “Asymmetric Tandem Reduction of 2-(Aroylmethyl)quinolines with Phosphine-Free Ru-TsDPEN Catalyst”, Synlett, 2011, 7, 939-942.


10. Zhen Wang, Tianli Wang, Weijun Yao, Yixin Lu*, “Phosphine-Catalyzed Enantioselective [4 + 2] Annulation of o-Quinone Methides with Allene Ketones”, Org. Lett., 2017, 19, 4126-4129.


9. Xiaoyu Han, Weijun Yao, Tianli Wang, Yong Ren Tan, Ziyu Yan, Jacek. Kwiatkowski, Yixin. Lu*, “Asymmetric Synthesis of Spiropyrazolones through Phosphine-Catalyzed [4 + 1] Annulation”, Angew. Chem. Int. Ed., 2014, 53, 5643-5647.


8. Zi-Yuan Ding, Tianli Wang, Yan-Mei He, Fei Chen, Hai-Feng Zhou, Qing-Hua Fan*,  Qingxiang Guo*, and Albert S. C. Chan, “Highly Enantioselective Synthesis of Chiral Tetrahydroquinolines and Tetrahydroisoquinolines by Ruthenium-Catalyzed Asymmetric Hydrogenation in Ionic Liquid”, Adv. Synth. Catal., 2013, 355, 3727-3735.


7. Fei Chen, Tianli Wang, Yanmei He, Ziyuan Ding, Zhiwei Li, Lijin Xu and Qing-Hua Fan*, "Asymmetric Hydrogenation of N-Alkyl Ketimines with Phosphine-Free, Chiral, Cationic Ru-MsDPEN Catalysts", Chem. –Eur. J., 2011, 17, 1109-1113.


6. Zhi-Wei Li, Tianli Wang, Yan-Mei He, Zhi-Jian Wang, Qing-Hua Fan*, Jie Pan and Li-Jin Xu*, "Air-Stable and Phosphine-Free Iridium Catalysts for Highly Enantioselective Hydrogenation of Quinoline Derivatives", Org. Lett., 2008, 10, 5265-5268.  


5. Haifeng Zhou, Zhiwei Li, Zhijian Wang, Tianli Wang, Lijin Xu, Yanmei He, Qing-Hua Fan*, Jie Pan, Lianquan Gu and Albert S. C. Chan*, "Hydrogenation of Quinolines Using a Recyclable Phosphine-Free Chiral Cationic Ruthenium Catalyst: Enhancement of Catalyst Stability and Selectivity in an Ionic Liquid",  Angew. Chem. Int. Ed., 2008, 47, 8464-8467.


4. Zhi-Jian Wang, Hai-Feng Zhou, Tianli Wang, Yan-Mei He, Qing-Hua Fan*, "Highly Enantioselective Hydrogenation of Quinolines under Solvent-Free or Highly Concentrated Conditions", Green Chem., 2009, 11, 767-769.


3. Fei Chen, Ziyuan Ding, Jie Qin, Tianli Wang, Yanmei He and Qing-Hua Fan*, "Highly Effective Asymmetric Hydrogenation of Cyclic N-Alkyl Imines with Chiral Cationic Ru-MsDPEN Catalysts", Org. Lett., 2011, 13, 4348-4351.


2. Weijun Tang, Yawei Sun, Lijin Xu* Tianli Wang, Qing-Hua Fan, Kim-Hung Lam and Albert S. C. Chan, "Highly Efficient and Enantioselective Hydrogenation of Quinolines and Pyridines with Ir-Difluorphos Catalyst", Org. Biomol. Chem., 2010, 8, 3464-3471.


1. Fei Chen, Ziyuan Ding, Yanmei He, Jie Qin, Tianli Wang and Qing-Hua Fan*, "Asymmetric Hydrogenation of N-Alkyl and N-Aryl Ketimines using Chiral CationicRu(Diamine) Complexes as Catalysts: The Counteranion and Solvent Effects, and Substrate Scope", Tetrahedron, 2012, 68, 5248-5257.


 

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