Research Interests:
Rare-earth metal catalysis, Chiral Lewis acid catalysis, The synthesis of bioactive molecules
Education And Academic Experience：
2004.9‒2008.6: B.Sc., College of Chemistry, Sichuan University, China (with Prof. Dr. Xiaoming Feng)
2008.9‒2013.6: Ph.D., College of Chemistry, Sichuan University, China (with Prof. Xiaoming Feng)
2013.11‒2016.2: Humboldt Postdoctoral Fellow at Institute for Organic Chemistry, RWTH Aachen University (with Prof. Carsten Bolm)
2016.7‒2017.12: Postdoctoral Fellow at Organisch-Chemisches Institut, Westfälische Wilhelms-Universität Münster (Prof. Gerhard Erker)
2018.1‒present: Professor, College of Chemistry, Sichuan University, Chengdu, China
Honors and Awards：
2013 Humboldt Research Fellowship for Postdoctoral Researchers
2019 "Thousand Talents Program" of Sichuan Province
2019 First Prize of Natural Science of Science Research Famous Achievement Award in Higher Institution (Fourth)
2021 Thieme Chemistry Journals Award
Editorial/Advisory Board Memberships：
Editorial Board of Chinese Chemical Letters
Publications:
1. Tan, Zheng.; Chen, L.; Li, L. Y.; Li, Y. Z.; Luo, Y.; Wang, F.; Dong, S. X.*; Feng, X M.* Asymmetric Synthesis of α-Methylene-γ-butyrolactones via Tandem Allylboration/Lactonization: a Kinetic Resolution Process. Angew. Chem. Int. Ed. 2023, 62, e202306146.
2. Li, D. W.; Ning, L. C.; Luo, Q. L.; Wang, S. Y.; Feng, X. M.; Dong, S. X.*. C-H alkylation of pyridines with olefins catalyzed by imidazolin-2-iminato-ligated rare-earth alkyl complexes. Sci. China. Chem. 2023, 66, 1804.
3. Wang. S. Y.; Zhu, C. H.; Ning, L. C.; Li, D. W.; Feng, X. M; Dong, S. X.* Regioselective C-H alkylation of anisoles with olefins by cationic imidazolin-2-iminato scandium(III) alkyl complexes. Chem. Sci. 2023, 14. 3132 (cover picture).
4. Zhu, C. H.; Zhou, Y. Q.; Yang, J.; Feng, X. M.; Dong, S. X.* Lanthanide-catalyzed regio- and enantioselective hydrosilylation of aryl-substituted terminal and internal alkenes. Org. Chem. Front. 2023, 10, 1263.
5. Wang, S. J.; Zhang, C.; F.; Li, D.; Zhou, Y. Q.; Su, Z. S.; Feng, X. M.; Dong, S. X.* New Chiral N-Heterocyclic Olefin Bifunctional Organocatalysis in α-Functionalization of β-Ketoesters, Sci. China. Chem. 2023, 66, 147.
6. Dong, S. X.; Liu, X. H.*; Feng, X. M.* Asymmetric Catalytic Rearrangements with a-Diazocarbonyl Compounds, Acc. Chem. Res. 2022, 55, 415. (cover picture).
7. Lin, Q. C.; Zheng, S. J.; Chen, L.; Wu, J.; Li, Z. J.; Liu, P. Z.; Dong, S. X.*; Liu, X. H.; Peng, Q.*; Feng, X. M.* Catalytic Regio- and Enantioselective Protonation for the Synthesis of Chiral Allenes: Synergistic Effect of the Counterion and Water. Angew. Chem. Int. Ed. 2022, 61, e202203650 (cover picture).
8. Wang, Y.; Yihuo, A. Y.; Wang, L. F. Dong, S. X.*; Feng, X. M.* Catalytic Asymmetric Synthesis of Chiral Azo Compounds via Interrupted Japp–Klingemann Reaction with Aryldiazonium Salts, Sci. China Chem. 2022, 65, 546.
9. Dong, P.; Li, Z. J.; Liu, X. H.; Dong, S. X.*; Feng, X. M.* Asymmetric Synthesis of Polycyclic Spiroindolines via the Dy-catalyzed Cascade Reaction of 3-(2-Isocyanoethyl)indoles with Aziridines, Org. Chem. Front. 2022, 9, 4591.
10. Tang, X. X.; Su, Z. S.; Lin, Q. C.; Lin, L. L.; Dong, S. X.*; Feng, X. M.* Asymmetric Catalytic α-Selective Allylation of Ketones with Allyltrifluoroborates using Dual-functional Chiral InIII/N,N′-dioxide Complex, Chin. J. Chem. 2022, 40, 1793.
11. Zhong, X.; Tan, J. Q.; Qiao, J. L.; Zhou, Y. Q.; Lv, C. D.; Su, Z. S.; Dong, S. X.*; Feng, X. M.* Catalytic Asymmetric Synthesis of Spirocyclobutyl Oxindoles and Beyond via [2+2] Cycloaddition and Sequential Transformations, Chem. Sci. 2021, 12, 9991.
12. Xu, C. R.; Qiao, J. L.; Dong, S. X.*; Zhou, Y. Q.; Liu, X. H.; Feng, X. M.* Asymmetric Synthesis of Dihydro-1,3-Dioxepines by Rh(II)/Sm(III) Relay Catalytic Three-Component Tandem [4+3]-Cycloaddition, Chem. Sci. 2021, 12, 5458. This article is part of the themed collection: 2021 Chemical Science HOT Article Collection. Highlighted by Synfacts 2021, 17, 0518.
13. Xiao, W. L.; Mo, Y. H.; Guo, J.; Su, Z. S.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Catalytic Enantioselective Synthesis of Macrodiolides and their Application in Chiral Recognition, Chem. Sci., 2021, 12, 2940.
14. Xiong, Q.; Luo, Q. L.; Zhang, T. H.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Catalytic Asymmetric Multicomponent Reaction of Isocyanide, Isothiocyanate and Alkylidene Malonates, Chem. Commun. 2021, 57, 7288.
15. Tang, X. X.; Su, Z. S., Yan, L. Q.; Tang, Q.; Dong, S. X.*; Lin, L. L. Xiaoming Feng, X. M.* Diastereo- and Enantioselective Synthesis of 3-Allyl-3-hydroxyoxindoles via Allylation of Isatins, Org. Lett. 2021, 23, 8419.
16. Dong, P.; Chen, L.; Yang, Z. D.; Dong, S. X.*; Feng, X. M.* Asymmetric Cycloisomerization/[3+2] Cycloaddition for Synthesis of Chiral Spiroisobenzofuran-1,3'-pyrrolidine Derivatives, Org. Chem. Front. 2021, 8, 6874.
17. Chen, Y. S.; Liu, Y.; Li, Z. J.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Tandem Insertion/[1,3]-Rearrangement: Highly Enantioselective Construction of a-Aminoketones, Angew. Chem. Int. Ed. 2020, 59, 8052.
18. Wang, F.; Feng, L. L.; Dong, S. X.*; Liu, X. H.; Feng, X. M.* Chiral N,N′-Dioxide-Iron(III)-Catalyzed Asymmetric Sulfoxidation with Hydrogen Peroxide, Chem. Commun. 2020, 56, 3233.
19. Li, D. W.; Wang, S. J.; Ge, S. L.; Dong, S. X.*; Feng, X. M. Asymmetric Synthesis of Axially Chiral Anilides via Organocatalytic Atroposelective N-Acylation, Org. Lett. 2020, 22, 5331.
20. Dong, S. X.; Daniliuc, C. G.; Kehr, G.; Erker, G.* Formation of Active Cyclic Five-membered Frustrated Phosphane/Borane Lewis Pairs and their Cycloaddition Reactions, Chem. Eur. J. 2020, 26, 745.
21. Luo, Y.; Zhang, H.; Wang, S. Y.; Zhou, Y. Q.; Dong, S. X.*; Feng, X. M.* Asymmetric Catalytic Diverse Ring Opening/Cycloadditions of Cyclobutenones with (E)-Alkenyloxindoles and (E)-Dioxopyrrolidines, Org. Lett. 2020, 22, 2645.
22. Ge, S. L.; Zhang, Y. Y.; Tan, Z.; Li, D. W.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Bimetallic Catalytic Tandem Reaction of Acyclic Enynones: Enantioselective Access to Tetrahydrobenzofuran Derivatives, Org. Lett. 2020, 22, 3551. Highlighted by Synfacts, 2020, 16, 0820.
23. Tang, Q.; Fu, K.; Ruan, P. R.; Dong, S. X.*; Su, Z. S; Liu, X. H.; Feng, X. M.* Asymmetric Catalytic Formal 1,4-Allylation of β,γ-Unsaturated α-Ketoesters via Allylboration/Oxy-Cope Rearrangement, Angew. Chem. Int. Ed. 2019, 58, 11846.
24. Xiong, Q. Li, G. L.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Enantioselective Synthesis of Hydrothiazole Derivatives via an Isocyanide-Based Multicomponent Reaction, Org. Lett. 2019, 21, 8771.
25. Liu, W.; Zhou, P. F.; Lang, J. W.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, A Nickel(II)-Catalyzed Asymmetric Intramolecular Alder-ene Reaction of 1,7-Dienes, Chem. Commun. 2019, 55, 4479.
26. Li, X. Q.; Xiong, Q.; Guan, M. M.; Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Divergent Synthesis of Enantioenriched β-Functional Amines via Desymmetrization of meso-Aziridines with Isocyanides, Org. Lett. 2019, 21, 6096.
27. Dong, S. X.; Feng, X. M.; Liu, X. H.* Chiral Guanidine and Their Derivatives in Asymmetric Synthesis, Chem. Soc. Rev. 2018, 47, 8525.
28. Zhong, X.; Tang, Q., Zhou, P. F.; Zhong, Z. W. Dong, S. X.*; Liu, X. H.; Feng, X. M.*, Asymmetric Synthesis of Polysubstituted Methylenecyclobutanes via Catalytic [2+2] Cycloaddition Reaction of N-Allenamides, Chem. Commun. 2018, 54, 10511. Highlighted by Synfacts 2018, 14, 1154.
Before SCU:
29. Dong, S. X.; Frings, M.; Cheng, H. C.; Wen, J.; Zhang, D.; Rabbe, G.; Bolm, C.* Organocatalytic Kinetic Resolution of Sulfoximines. J. Am. Chem. Soc. 2016, 138, 2166. Highlight by Synfacts 2016, 12, 634.
30. Dong, S. X.; Liu X. H.*; Zhu, Y.; He, P.; Lin, L. L.; Feng, X. M.* Organocatalytic Oxyamination of Azlactones: Kinetic Resolution of Oxaziridines and Asymmetric Synthesis of Oxazolin-4-ones. J. Am. Chem. Soc. 2013, 135, 10026. Highlight by Synfacts (2013, 1006).
31. Dong, S. X.; Liu, X. H.; Chen, X. H.; Mei, F.; Gao, B.; Lin, L. L.; Feng, X. M.* Chiral Bisguanidine-Catalyzed Inverse-Electron-Demand Hetero-Diels-Alder Reaction of Chalcones with Azlactones. J. Am. Chem. Soc. 2010, 132, 10650. Highlight by Synfacts (2010, 1105).
32. Dong, S. X.; Frings, M.; Zhang, D.; Guo. Q. Q.; Danilliuc, C. G.; Cheng, H. C.; Bolm, C.* Organocatalytic Asymmetric Synthesis of trans-γ-Lactams. Chem. Eur. J. 2017, 23, 13888.
33. Dong, S. X.; Wang, L.; Wang, T.; Daniliuc, C. G.; Brinkkötter, M.; Eckert, H.; Kehra. G.; Erker, G. Formation and Reactions of Active Five-membered Phosphane/borane Frustrated Lewis Pair Ring Systems. Dalton Trans. 2018, 47, 4449.
34. Dong, S. X.; Liu, X. H*.; Zhang, Y. L.; Lin, L. L.; Feng, X. M *. Asymmetric Synthesis of 3,4-Diaminochroman-2-ones Promoted by Guanidine and Bisguanidium Salt. Org. Lett. 2011, 13, 5060.
35. Liu, X. H.; Dong, S. X.; Lin, L. L.; Feng, X. M.* Chiral Amino Acids-Derived Catalysts and Ligands. Chin. J. Chem, 2018, 36, 791.
36. Guo, J.; Dong, S. X.; Zhang, Y. L.; Kuang, Y. L.; Feng, X. M.* Chiral Scandium(III)-Catalyzed Enantioselective α-Arylation of N-Unprotected 3-Substituted Oxindoles with Diaryliodonium Salts. Angew. Chem., Int. Ed. 2013, 52, 10245. Highlight by Synfacts (2013, 1262).
37. Wang, L.; Dong, S. X.; Daniliuc, C. G.; Liu, L.; Grimme, S.; Knitsch, R.; Eckert, H.; Hansen, M. R.; Kehra. G.; Erker, G. Formation of Macrocyclic Ring Systems by Carbonylation of Trifunctional P/B/B Frustrated Lewis Pairs. Chem. Sci. 2018, 9, 1544.
